I was talking to a friend of mine about this a couple of weeks ago, and she made the point that we were 'Programmed' (pun intended) to respond to life situations in the worst possible way-- whether it is endless self-criticism and self-analysis, whether it is "being open and honest" to people that we should not be that way with, trusting those who do not deserve our trust, suspicious of those that do, "confronting" others (either to show that we are 'strong' or that we 'really care'). This all happened for us during formative, child-development years. Our socialization processes were fucked, and when you combine that with the constant drilling into our heads the lies of "you'll die without Straight" it became a self-fulfilling prophecy in all too many cases. I don't think I had any self-esteem issues before Straight, other than normal teenage-type stuff, but once they "diagnosed" me and drilled into my head that I had a "low self-opinion", I damn sure got one.