Keep in mind that one of the first things that resulted from the economic downturn early in the 20th century was a rebellion against prohibition.
Reason has a
good article online right now about how the number of companies that are doing random on the job testing is falling, and how ineffective drug testing is in the first place.
Prohibition has never worked, and it will continue to reveal itself as a failing policy, and become far more obvious in its failure as the economic situation worsens.
The Bush Tax cuts, which overwhelmingly favor the top 1% of taxpayers, along with the huge runup in Federal spending on the military will result in massive budget deficits which will in turn force interest rates higher- tighening the debt markets and making it harder and harder for business' already saddled with huge debt loads to refinance their bonds and other corporate debts- all of this points to a period of massive deflation, and potential recession or depression.
And the last depression led to one of the most liberal periods in the history of the country. The greatest atrocities are almost always commited at or near the end of a war, and so I think the end of the drug war may well be in sight.