oh yeah agreed. and i thought i was smart about it lol really only focused on researching "illegal" drugs that i put in my body though. wasnt even considering nor had i even paid much attention to what has been going on in the pharma industry since the mid 80s.
i only took methadone once, last november. i was ill and in a lot of pain. that drug almost killed me lol (thats anther story) but it damn sure might have saved my life too. I had a friend send me two, i hadn't slept in weeks and was damn near delirious. it removed the pain completely and i slept for like 20 hours. was able to clear my head enough to realize hmm maybe i should really go to the hospital now. lol yeah that was an adventure! 
I hear ya. At first, it saved mine. No real side effects, took care of the pain while allowing me to function. It was great. Until I had to stop.
And i meant to write "methadone was the hardest for me. " I'm not discounting what others have been through with various pharmaceuticals.
yeah im glad i didn't require to stay on anything that strong. as to how it almost killed me.. my friend sent me two like i mentioned. he told me to take either about 1/4 of a pill or the whole thing. so i was like fuck it ill take 1/2 lol . course he knew if i took only 1/4 i probably would have been able to function, but any more then that, if you happen to "wake up still high" can be quite dangerous. SO had i taken the WHOLE pill i never would have woken up.
But i woke up when i fell out of my chair and hit the floor. lol no pain though, i was just sitting there waiting and it never came. So I got up and went to the bathroom. I look in the mirror and i pass out. My face hits the ceramic sink and there i am looking in the mirror again. No blood, no pain, coulda cracked my head open. was in awe but too fucked up to fully appreciate what almost happened. I figured it would be best if i went back on the couch before i killed myself. so i did. lol